Anna O. explores the life of Bertha Pappenheim and birth of psychoanalysis. It depicts the therapeutic relationship of Fraulein Pappenheim with Dr. Josef Breuer, the Viennese general physician who treated her 'hysterical' condition by helping her to uncover her traumatic experiences and repressed memories and emotions, without resorting to the more conventional therapies of 'uterine manipulation', blood-letting, stimulation with electric eels, and water baths. Breuer discussed this treatment with the younger Freud. Fraulein Pappenheim's story does not end here, however. She subsequently became a major champion of women's and children's rights throughout Europe, until she and her work came under the deadly scrutiny of the Nazis.